It is amazing that a small peptide can interfere with PTEN protein interactions with the Serotonin receptor. We have been exploring the interactions of that peptide with PTEN. We published in the Journal of Neuroscience on changes in activity in cells and looked at docking possible confirmations that were derived from Replicate Exchange Molecular Dynamics Simulations.
J Neurosci. 2013 Jan 23;33(4):1615-30